{"product_id":"synergeia-vitamin-c-20-eff-tab","title":"Cross Pharma Synergeia Flavonoids - Dietary Supplement For Swollen \u0026amp; Tired Feet, 20 effervescent tablets","description":"\u003cp\u003eIt contributes to the normal formation of collagen for the functioning of blood vessels and the protection of cells from oxidative stress. The preparation is a combination of diosmin, hesperidin, troxerutin and vitamin C. Diosmin is a semi-synthetic phlebotropic drug (modified hesperidin), a member of the flavonoid family. Diosmin prolongs the vasoconstrictor effect of norepinephrine on the venous wall, resulting in an increase in venous tone and consequently a decrease in venous capacity, distensibility and stasis. Diosmin improves lymphatic drainage by increasing the frequency and intensity of contractions of the lymphatic system, increasing the total number of functional capillaries of the lymphatic system. Finally, diosmin reduces the expression of adhesion molecules on the endothelium (ICAM1, VCAM1), and inhibits the adhesion, migration and activation of leukocytes at the capillary level. This leads to a reduction in the release of inflammatory mediators, mainly oxygen free radicals and prostaglandins (PGE2, PGF2a). Oxerutins are flavonoids synthesized from rutin. They act on the smallest blood vessels (capillaries) by reducing microleakage of water and other substances through the walls. They reduce edema caused by diseases of the veins of the legs and relieve the usual associated symptoms, such as pain, fatigue, heavy legs and cramps. Ascorbic acid is an essential component of the human body. Ascorbic acid has a strong reducing effect. The metabolic role of ascorbic acid is multidimensional. In the intestine, it promotes the absorption of non-heme iron. It participates in the synthesis of hydroxyproline, corticosteroids and carnitine. It is a precursor of oxalates that are excreted by the kidneys. It is a powerful antioxidant factor in the metabolism of lipids, cell membranes and vitamins.\u003c\/p\u003e","brand":"CROSS","offers":[{"title":"Default Title","offer_id":40550774210746,"sku":"","price":13.09,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0582\/1543\/2378\/products\/20181105151919_cross_pharmaceuticals_synergeia_20_anavrazonta_diskia.jpg?v=1633083655","url":"https:\/\/thinkphirmacy.com\/en\/products\/synergeia-vitamin-c-20-eff-tab","provider":"Think Pharmacy","version":"1.0","type":"link"}